Modeling cell-to-cell spread of HIV-1 with logistic target cell growth
نویسندگان
چکیده
منابع مشابه
Macrophages and Cell-Cell Spread of HIV-1
Macrophages have been postulated to play an important role in the pathogenesis of HIV-1 infection. Their ability to cross the blood-brain barrier and their resistance to virus-induced cytopathic effects allows them to serve as reservoirs for long-term infection. Thus, exploring the mechanisms of virus transmission from macrophages to target cells such as other macrophages or T lymphocytes is ce...
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متن کاملA mathematical model of cell-to-cell spread of HIV-1 that includes a time delay.
We consider a two-dimensional model of cell-to-cell spread of HIV-1 in tissue cultures, assuming that infection is spread directly from infected cells to healthy cells and neglecting the effects of free virus. The intracellular incubation period is modeled by a gamma distribution and the model is a system of two differential equations with distributed delay, which includes the differential equa...
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ژورنال
عنوان ژورنال: Journal of Mathematical Analysis and Applications
سال: 2015
ISSN: 0022-247X
DOI: 10.1016/j.jmaa.2014.10.086